Phase separation of Nur77 mediates celastrol-induced mitophagy

nuri77Article The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome Fangrui Zhu,1,2,3,8 Juan Ma,1,2,3,8 Weitao Li,1,2,3,8 Qiannv Liu,1,2,3,8The mechanism of Nur77 regulating cell survival and apoptosis in CNS. Nur77 mediates cell apoptosis through caspase, endoplasmic reticulum stress, and mitochondrial autophagy, while